I am a research fellow and instructor at the Jan and Dan Neurological Research Insistute, affiliated with Baylor College of Medicine and Texas Children's Hospital. I am also a consultant for AstraZeneca's Center for Genomic Research. My research focuses on the use of human genetics and functional genomics to understand the mechanisms of human disease. I received my MD/PhD from Columbia University in 2021, where I trained under Dr. David Goldstein at the Institute for Genomic Medicine.
I am also the co-founder of MedChances, a website that provides free medical school admissions predictions. I am originally a native of Reno, Nevada.
 Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling
C Vasavda, ER Semenza, J Liew, R Kothari, RS Dhindsa, S Shanmukha, A Lin, R Tokhunts, C Ricco, AM Snowman, LK Albacarys, F Pastore, C Ripoli, C Grassi, E Barone, MD Kornberg, X Dong, BD Paul, SH Snyder. Science Signaling. (2022).
 Ancestry adjustment improves genome-wide estimates of regional intolerance
T Hayeck, N Stong, E Baugh, RS Dhindsa, TN Turner, A Malakar, Y Duan, I Ionita-Laza, DB Goldstein, AS Allen. Genetics. (2020).
 Association of ultra-rare coding variants with genetic generalized epilepsy: A case–control whole exome sequencing study
M Koko, JE Motelow, KE Stanley, DR Bobbili, RS Dhindsa, P May, Canadian Epilepsy Network, Epi4K Consortium, Epilepsy Phenome/Genome Project, EpiPGX Consortium, EuroEPINOMICS-CoGIE Consortium. Epilepsia. (2022).
 Cancer-driving mutations are enriched in genic regions intolerant to germline variation
D Vitsios*, RS Dhindsa*, J Mitchell, D Matelska, Z Zou, J Armenia, Q Wang, B Sidders, AR Harper, S Petrovski. BioRxiv. (2022).
 Assessing the contribution of rare-to-common protein-coding variants to circulating metabolic biomarker levels via 412,394 UK Biobank exome sequences
A Nag, L Middleton, RS Dhindsa, D Vitsios, E Wigmore, EL Allman, A Reznichenko, K Carss, KR Smith, Q Wang, B Challis, DS Paul, AR Harper, S Petrovski. MedRxiv. (2021).
 High-impact rare genetic variants in severe schizophrenia
AW Zoghbi, RS Dhindsa, TE Goldberg, A Mehralizade, JE Motelow,X Wang, A Alkelai, MB Harms, JA Lieberman, S Markx. PNAS. (2021).
 Human genetic evidence supports MAP3K15 inhibition as a therapeutic strategy for diabetes
A Nag*, RS Dhindsa*, AR Harper, D Vitsios, A Ahnmark, B Bilican, K Madeyski-Bengtson, B Zarrouki, Q Wang, K Smith, D Smith, B Challis, DS Paul, M Bohlooly-Y, M Snowden, D Baker, R Fritsche-Danielson, MN Pangalos, S Petrovski. medRxiv. (2021)
 Rare variant contribution to human disease in 281,104 UK Biobank exomes
Q Wang*, RS Dhindsa*, K. Carss*, AR Harper, A Nag, I Tachmazidou, D Vitsios, SVV Deevi, A Mackay, D Muthas, Michael Hühn, S Monkley, H Olsson, S Wasilewski, KR Smith, R March, A Platt, C Haefliger, S Petrovski. Nature. (2021).
 Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals
Epi25 Consortium. The American Journal of Human Genetics, (2021).
 Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis
RS Dhindsa, J Mattsson, A Nag, Q Wang, LV Wain, R Allen, EM Wigmore, K Ibanez, D Vitsios, SV Deevi, S Wasilewski, M Karlsson,G Lassi, H Olsson, D Muthas, S Monkley, A Mackay, L Murray, S Young, C Haefliger, FinnGen Consortium, TM Maher, MG Belvisi, G Jenkins, P Molyneaux, A Platt, S Petrovski. Communications Biology. (2021).
 Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning
D Vitsios, RS Dhindsa, L Middleton, AB Gussow, S Petrovski. Nature Communications. (2021).
 A Transcriptome‐Based Drug Discovery Paradigm for Neurodevelopmental Disorders
RS Dhindsa, AW Zoghbi, DK Krizay, C Vasavda, DB Goldstein. Annals of Neurology. (2021).
 TMPRSS2 Transcriptional Inhibition as a Therapeutic Strategy for COVID-19
X Wang, RS Dhindsa, G Povysil, A Zoghbi, J Motelow, J Hostyk, N Nickols, M Rettig, DB Goldstein. Preprints. (2020).
 Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
SA Dugger*, RS Dhindsa*, G Sampaio, E Rafikian, S Petri, J Teoh, J Ye, S Colombo, M Yang, M Boland, W Frankel, DB Goldstein. bioRxiv. (2020).
 Natural selection shapes codon usage in the human genome
RS Dhindsa, BR Copeland, AM Mustoe, DB Goldstein. American Journal of Human Genetics. (2020).
 Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals
Epi25 consortium. American Journal of Human Genetics. (2019).
 G protein-coupled potassium channels implicated in mouse and cellular models of GNB1 Encephalopathy
S Colombo, S Petri, B Shalomov, HP Reddy, G Tabak, RS Dhindsa, S Gelfman, S Teng, D Krizay, EE Rafikian, AK Bera, M Yang, MJ Boland, Y Peng, WN Frankel, N Dascal, DB Goldstein. bioRxiv. (2019).
 meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays
S Gelfman, Q Wang, Y Lu, D Hall, CD Bostick, RS Dhindsa, M Halvorsen, KM McSweeney, E Cotterill, T Edinburgh, MA Beaumont, WN Frankel, S Petrovski, AS Allen, MJ Boland, DB Goldstein, SJ Eglen. PLoS computational biology. (2018).
 Orion: detecting regions of the human non-coding genome that are intolerant to variation using population genetics
AB Gussow, BR Copeland, RS Dhindsa, Q Wang, S Petrovski, WH Majoros, AS Allen, DB Goldstein. PloS one. (2017).
 Molecular Architecture and Neurobiology of the Epilepsies
RS Dhindsa, DH Lowenstein, DB Goldstein. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. (2016).
 Schizophrenia: From genetics to physiology at last
RS Dhindsa, DB Goldstein. Nature. (2016).
 Genetic Discoveries Drive Molecular Analyses and Targeted Therapeutic Options in the Epilepsies
RS Dhindsa, DB Goldstein. Current neurology and neuroscience reports. (2015).
 Exome sequencing results in successful riboflavin treatment of a rapidly progressive neurological condition
S Petrovski, V Shashi, S Petrou, K Schoch, KM McSweeney, RS Dhindsa, B Krueger, R Crimian, LE Case, R Khalid, MA El-Dairi, Y Jiang, MA Mikati, DB Goldstein. Molecular Case Studies. (2015).
 Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios
X Zhu, S Petrovski, P Xie, EK Ruzzo, Y Lu, KM McSweeney, B Ben-Zeev, A Nissenkorn, Y Anikster, D Oz-Levi, RS Dhindsa, Y Hitomi, K Schoch, RC Spillmann, G Heimer, D Marek-Yagel, M Tzadok, Y Han, G Worley, J Goldstein, Y Jiang, D Lancet, E Pras, V Shashi, D McHale, AC Need, DB Goldstein. Genetics in Medicine. (2015).
 Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis.
RS Dhindsa, SS Bradrick, X Yao, EL Heinzen, S Petrovski, BJ Krueger, MR Johnson, WN Frankel, S Petrou, RM Boumil, DB Goldstein. Neurology Genetics. (2015).